Fight Acne with Postbiotics

Importance of Microbial Balance

Our skin is home to millions of bacteria, fungi, and viruses that make up our skin microbiome. This complex ecosystem plays a crucial role in our skin health, protecting against pathogens and environmental damage. Just like the gut microbiome, the skin microbiome needs a fine balance to function optimally. When this balance is disturbed, skin issues such as acne, eczema, and psoriasis can occur.

Acne

Acne is actually an inflammatory skin disease caused by increased sebum production, infection of the sebaceous glands and bacterial colonization of hair follicles by C. acnes.

The main causes of acne formation are: genes, hormones, hygiene, diet, emotional stress, physical stress, pollution..

Besides, 4 main factors interact in this formation mechanism

-Excessive sebum production

-Bacteria proliferation

-Inflammation

-Hyperkeratinization


NON INFLAMMATORY ACNE BLEMISHES: INFLAMMATORY ACNE BLEMISHES:

Although they are linked together in a vicious cycle, the “microbial” influence is thought to be the primary and most distinctive contributing element.

Let's go deeper into acne formation together with the skin microbiota...

Acne and Bacterial Imbalance

Acne is often associated with an overgrowth of a particular type of bacteria known as Cutibacterium acnes (C. acnes). However, this is only part of the story. While C.acnes is indeed present in greater numbers in acne-prone skin, it is also found in healthy skin.

The difference lies in the diversity and overall balance of the skin microbiome. Acne-prone skin tends to have less bacterial diversity, and this lack of balance seems to contribute to inflammation and acne breakouts.

Get ready to new galaxy of skincare with the latest buzzword:

Postbiotics

Enter postbiotics. While you may have heard of “probiotics” (live beneficial bacteria) and “prebiotics” (food for good bacteria), “postbiotics” might be a new term.

Postbiotics are essentially the byproducts of probiotic bacterial fermentation. These include enzymes, peptides, teichoic acid, and other metabolic compounds that have various beneficial effects on our health.

In skincare, postbiotics can help restore the skin's microbiome balance, reduce inflammation, and protect the skin barrier. They can be particularly beneficial for acne-prone skin, helping to reduce the overgrowth of C. acnes and promote a more diverse and balanced skin microbiome.

Good Bacteria: S. epidermidis

One of the beneficial bacteria found on our skin is Staphylococcus epidermidis (S. epidermidis). This bacterium is a key player in maintaining the balance of our skin's microbiome. Interestingly, S. epidermidis helps suppress the growth of C.acnes.

Studies show that the presence of S. epidermidis in the skin can help restore the skin's microbiome balance and reduce acne inflammation.

But simply reducing the amount of C. acnes is not the only way to clear Acne!

Let's talk about the technology developed by Active Bioworks at this point!

At Active Bioworks, we know that postbiotic ingredients provide a helpful approach to acne suppression and balancing the overall skin microbiota, addressing the root cause of the problem: bacterial imbalance.

This is where sebum Active 4D comes in...

GET RID OF

ACNE

WITH

SEBUMACTIVE 4D


BENEFITS

Regulates Sebum Production in Skin

Pore-minimizing (Astringent)

Reduce Irritation because of Acne.

Balanced Microbiome in Skin.

Inhibition of Acne related bacteria.

Final Thoughts

In conclusion, maintaining a healthy and balanced skin microbiome is key to preventing and treating acne. Postbiotics, along with beneficial bacteria like S. epidermidis, offer a promising solution to rebalance our skin's microbiome and address acne at its root.

As our understanding of the skin microbiome continues to expand, we can look forward to more innovative and effective treatments for acne and other skin issues...

Have a nice and “beautiful” day!

Please don’t hesitate to reach us for more: hello@activebioworks.com

Sales Force, Active Bioworks

REFERENCES

Bifulco, Guglielmo, et al. "Postbiotics for hair and scalp microbiome balance." dermatitis 5: 8.

Arora, Rashmi, et al. "Evolving Advances in the Cosmetic Use of Probiotics and Postbiotics: Health, Regulatory and Marketing Aspects." Current Pharmaceutical Biotechnology (2024).

Dréno, Brigitte, et al. "Cutibacterium acnes (Propionibacterium acnes) and acne vulgaris: a brief look at the latest updates." Journal of the European Academy of Dermatology and Venereology 32 (2018): 5-14.

Dessinioti, Clio, and Andreas Katsambas. "Propionibacterium acnes and antimicrobial resistance in acne." Clinics in dermatology 35.2 (2017): 163-167.

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